Antimuscarinic medication for an overactive bladder:
- Vesicare (Solifenacin) 5mg / 10mg once daily
- Detrusitol XL (Tolterodine) 4mg once daily
- Lyrinel XL (Oxybutinin) 5mg / 10mg once daily
- Kentera Patch (Oxybutinin transdermal) applied every 3-4 days
- Toviaz (Fesoterodine) 4mg and 8mg once daily
- Regurin (Trospium chloride) 20mg BD
- Emselix (Darifenicin) 7.4 / 15mg once daily
Beta-3 adrenergic receptor agonist medication:
- Mirabegron (Betmiga) 25mg / 50mg once daily
- Antimuscarinic agents and beta3-receptor agonists act to relax the detrusor muscle of the bladder wall.
- Most patients will report a reduction to their symptoms within the first 2 to 4 weeks of use.
- The need for continuing drug therapy should be reviewed after 3 to 6 months. If taken long term, they should be reviewed yearly.
- Must not be given when person has incomplete emptying or urinary retention as it may make this worse.
- Consult your local formulary for choice of drug.
Page last reviewed: 31 Jan 2022
