Stroke Training and Awareness Resources (STARs)


16: Update and decisions

Now 8hrs 20 mins (500 mins) since last seen well, BP currently 190/110, NIHSS unchanged at 21.

What would you do next?

Request further advanced imaging (e.g. CTP, MRI, MRP) to guide treatment?

CTP shows penumbra >15ml, core <70ml, mismatch ratio greater than 1.8,  favourable towards treatment.

Any BP intervention?

  • No BP intervention
  • Lower SBP to <180mmHg before bolus
  • Start lowering BP, but give bolus before attaining target

All of our experienced colleagues recommended lowering BP before giving lysis.

Any lysis intervention?

  • No lysis
  • Treat with alteplase 0.9mg/kg
  • Treat with alteplase 0.6mg/kg
  • Treat with tenecteplase

4/5 experienced colleagues recommended alteplase 0.9mg/kg and 1/5 recommended no lysis.

Refer for thrombectomy?

  • Yes
  • No

All of our experienced colleagues recommended referral for thrombectomy.