Which of the following are correct about cholesterol reduction?
Correct statements
- Statins should be used cautiously in patients with excess alcohol intake or liver impairment
- There is an interaction with statins and grapefruit juice
- The risk of myopathy with statins is dose related
- The benefits of statins are dose related
- Headache and sleep disturbance are recognised side effects of statins
- Statins reduce vascular risks and total mortality irrespective of the initial cholesterol concentration
Incorrect statements
- Myalgia can occur but does not herald any serious problems and so statins can usually be continued
- Statins are much more effective if used in pairs, e.g. simvastatin + atorvastatin together
- Pregnancy is not a contra-indication to statin use
- Statins should not be used. Contraception needed during treatment and 1 month after statin use.
- The greater the low-density lipoprotein (LDL) cholesterol the lower the risk of stroke
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Page last reviewed: 25 Feb 2022
