Absolute risks

The absolute risks are higher than average for stroke or TIA patients who have:

  • prior history of heart attacks, TIAs, previous strokes and peripheral vascular disease
  • diabetes
  • atrial fibrillation
  • carotid artery stenosis

Risks are generally lower

  • if no cause of stroke or TIA is identified

Understanding risk

Risk of stroke after TIA / minor stroke

The red men represent people having strokes. 10 people will have a stroke in the 7 days after a TIA – a 10% risk. The daily risk of stroke falls over the next few months. About another 5 people (5%) will have a stroke between 7 and 30 days, another 5% between 30 days and 90 days and another 5% between 90 days and the end of the first year. Therefore, 25 (25%) will have a stroke over the first year but most occur in the early period.

Where to access smoking cessation support

Stop smoking services include:

  • NHS Smoking Helpline
  • Smoking cessation groups – held in health centres, community centres, and workplaces
  • Self referral or referral by health professional
  • Specialist smoking cessation nurses available in acute hospitals to support patients
  • NHS Specialist training advisers available who provide:
    • One-to-one support
    • Help in making personalised quit date
    • Ongoing support and encouragement
    • Relaxation and stress management techniques
    • Advice on habit-breaking, healthy eating and exercise
  • Community pharmacy smoking cessation service:
    • Pharmacies provide 12 weeks NRT and brief support
    • Clients can register for this service at any time by visiting the pharmacy of their choice

Useful websites:

Help to stop smoking

  • Nicotine Replacement Therapies (NRT) include – patches, lozenges, gum, nasal sprays, inhalers and tablets.
  • After stroke NRT should be started under medical supervision and treatment can last up to 3 months.
  • It is important to realise that the risk of smoking is far greater than the risk of using NRT after stroke.
  • Champix – this is a non-nicotine medication to help reduce the cravings and withdrawal symptoms and it also reduces the satisfaction gained from cigarettes
  • Zyban – it works on neurotransmitters in the brain to reduce nicotine cravings and withdrawal reactions.
  • The main reason why many smokers find it difficult to stop is nicotine dependence. Nicotine deprivation precipitates a withdrawal syndrome producing both physical symptoms and mood disturbances. These include mouth ulcers, concentration, irritability and urges to smoke.
  • The occurrence of these symptoms, especially urges to smoke and depressed mood, can lead to relapses early in a quit attempt.
  • As a healthcare professional providing smokers with signposting to smoking cessation services and  providing ongoing support can be pivotal to their success.
  • E-cigarette (or vaping) is a form of nicotine replacement therapy. E-cigarettes seem to be less harmful than smoking tobacco. However the long-term effects of smoking e-cigarettes have not yet been fully established. Current advice in Scotland is that vaping or e-cigarettes have less overall risk but they are not currently prescribed to people who wish to stop smoking. If a person chooses to use e-cigarettes, it should be as a stepping stone to quitting.
  • Smoking tobacco and using e-cigarettes together (dual usage) is not recommended as there is no benefit. 

For more information on smoking cessation visit: NHS stop smoking services

For more information on e-cigarettes visit: https://www.gov.scot/policies/smoking/electronic-cigarettes/

It’s never too late to stop

Stopping smoking is one of the best things a person can do for their health. It not only reduces the risk of stroke it also reduces the risk of other serious health conditions including: heart disease, chronic obstructive pulmonary disease (COPD) and cancer.

Benefits of not smoking:

  • After 1 year the risk of a heart attack is HALF that of a smoker
  • After 5 years the risk of stroke has fallen to the same as someone who has never smoked
  • After 10 years the risk of lung cancer has fallen to Half that of a smoker
  • After 15 years the risk of heart attack falls to the same as someone who has never smoked

For more information see CHSS: Stopping smoking essential guide.

Smoking

Evidence of stroke risk

Smoking is a significant public health issue in Scotland and a leading cause of preventable ill health, premature death and disability (Public Health Scotland (PHS) and people who smoke are twice as likely to suffer a stroke compared to non smokers (NHS Greater Glasgow & Clyde).

Smoking:

  • Has an overall increased risk of stroke compared with non smokers and former smokers (Pan et al 2019)
  • With increased cigarette consumption the risk of stroke is increased by 12% for each increment of 5 cigarettes per day (Pan et al 2019)
  • If you smoke 20 cigarettes a day you are 6 times more likely to have a stroke compared
    to a non smoker (CHSS 2019)
  • The risk associated is present at all ages, in both sexes and among different racial/ethnic groups
  • Passive smoking increases stroke risk by 45% (Pan et al 2019)
  • Smoking rates are still highest in the most deprived areas, with 35% of people living in the most deprived areas of Scotland smoking compared to 10% in the least deprived areas (PHS)
  • Smoking also carries the risk of developing other conditions such as cancer and respiratory (lung) disease
  • Smoking cessation and avoidance of second-hand/passive smoking are important strategies in the prevention of stroke and stroke recurrence (Stroke Association 2017)

Relationship to stroke risk

Carbon monoxide, a poisonous gas found in tobacco smoke, makes it easier for cholesterol to pass through into blood vessels & cause a fatty build up; which can lead to increased risk of heart disease and stroke.

Smoking:

  • Increases the risk of high blood pressure – a major risk factor to stroke (Stroke Association 2017)
  • Makes the smooth lining of blood vessels rough which encourages the build-up of atheroma, the fatty material that narrows and blocks vessels
  • Increases the amount of fibrinogen in the blood and makes blood stickier, increasing the chance of blood clots forming which cause strokes

Learn more about RCTs

RCTs follow a standard design, which randomly allocates patients to one of two or more treatment groups. The standard design for an RCT is illustrated in this flow diagram; click on each item for more information.