The absolute risks are higher than average for stroke or TIA patients who have:
- prior history of heart attacks, TIAs, previous strokes and peripheral vascular disease
- diabetes
- atrial fibrillation
- carotid artery stenosis
Risks are generally lower
- if no cause of stroke or TIA is identified
Risk of stroke after TIA / minor stroke
The red men represent people having strokes. 10 people will have a stroke in the 7 days after a TIA – a 10% risk. The daily risk of stroke falls over the next few months. About another 5 people (5%) will have a stroke between 7 and 30 days, another 5% between 30 days and 90 days and another 5% between 90 days and the end of the first year. Therefore, 25 (25%) will have a stroke over the first year but most occur in the early period.
- Nicotine Replacement Therapies (NRT) include – patches, lozenges, gum, nasal sprays, inhalers and tablets.
- After stroke NRT should be started under medical supervision and treatment can last up to 3 months.
- It is important to realise that the risk of smoking is far greater than the risk of using NRT after stroke.
- Champix – this is a non-nicotine medication to help reduce the cravings and withdrawal symptoms and it also reduces the satisfaction gained from cigarettes
- Zyban – it works on neurotransmitters in the brain to reduce nicotine cravings and withdrawal reactions.
- The main reason why many smokers find it difficult to stop is nicotine dependence. Nicotine deprivation precipitates a withdrawal syndrome producing both physical symptoms and mood disturbances. These include mouth ulcers, concentration, irritability and urges to smoke.
- The occurrence of these symptoms, especially urges to smoke and depressed mood, can lead to relapses early in a quit attempt.
- As a healthcare professional providing smokers with signposting to smoking cessation services and providing ongoing support can be pivotal to their success.
- E-cigarette (or vaping) is a form of nicotine replacement therapy. E-cigarettes seem to be less harmful than smoking tobacco. However the long-term effects of smoking e-cigarettes have not yet been fully established. Current advice in Scotland is that vaping or e-cigarettes have less overall risk but they are not currently prescribed to people who wish to stop smoking. If a person chooses to use e-cigarettes, it should be as a stepping stone to quitting.
- Smoking tobacco and using e-cigarettes together (dual usage) is not recommended as there is no benefit.
For more information on smoking cessation visit: NHS stop smoking services
For more information on e-cigarettes visit: https://www.gov.scot/policies/smoking/electronic-cigarettes/
Stopping smoking is one of the best things a person can do for their health. It not only reduces the risk of stroke it also reduces the risk of other serious health conditions including: heart disease, chronic obstructive pulmonary disease (COPD) and cancer.
Benefits of not smoking:
- After 1 year the risk of a heart attack is HALF that of a smoker
- After 5 years the risk of stroke has fallen to the same as someone who has never smoked
- After 10 years the risk of lung cancer has fallen to Half that of a smoker
- After 15 years the risk of heart attack falls to the same as someone who has never smoked
For more information see CHSS: Stopping smoking essential guide.
Evidence of stroke risk
Smoking is a significant public health issue in Scotland and a leading cause of preventable ill health, premature death and disability (Public Health Scotland (PHS) and people who smoke are twice as likely to suffer a stroke compared to non smokers (NHS Greater Glasgow & Clyde).
Smoking:
- Has an overall increased risk of stroke compared with non smokers and former smokers (Pan et al 2019)
- With increased cigarette consumption the risk of stroke is increased by 12% for each increment of 5 cigarettes per day (Pan et al 2019)
- If you smoke 20 cigarettes a day you are 6 times more likely to have a stroke compared
to a non smoker (CHSS 2019)
- The risk associated is present at all ages, in both sexes and among different racial/ethnic groups
- Passive smoking increases stroke risk by 45% (Pan et al 2019)
- Smoking rates are still highest in the most deprived areas, with 35% of people living in the most deprived areas of Scotland smoking compared to 10% in the least deprived areas (PHS)
- Smoking also carries the risk of developing other conditions such as cancer and respiratory (lung) disease
- Smoking cessation and avoidance of second-hand/passive smoking are important strategies in the prevention of stroke and stroke recurrence (Stroke Association 2017)
Relationship to stroke risk
Carbon monoxide, a poisonous gas found in tobacco smoke, makes it easier for cholesterol to pass through into blood vessels & cause a fatty build up; which can lead to increased risk of heart disease and stroke.
Smoking:
- Increases the risk of high blood pressure – a major risk factor to stroke (Stroke Association 2017)
- Makes the smooth lining of blood vessels rough which encourages the build-up of atheroma, the fatty material that narrows and blocks vessels
- Increases the amount of fibrinogen in the blood and makes blood stickier, increasing the chance of blood clots forming which cause strokes
There are a number of things which must be in place before a study can be carried out.
RCTs follow a standard design, which randomly allocates patients to one of two or more treatment groups. The standard design for an RCT is illustrated in this flow diagram; click on each item for more information.