Heart Education Awareness Resource and Training through eLearning (HEARTe)


Margaret’s management

A management plan is discussed and drawn up with Margaret.

Immediate Lifestyle Other considerations
  • Discontinue medications causing QT prolongation (Trimethoprim) & avoidance of QT prolonging drugs (www.crediblemeds.org)
  • Start beta-blocker (Bisoprolol to Nadolol)
  • Electrolytes (especially K
  • Monitor for ongoing arrhythmia
  • Long QT1 – avoid strenuous exercise and strenuous swimming
  • Long QT2 – less adrenergically mediated, avoid exposure to loud noises

(There may be overlap within each long QT type so the general advice is applied to all)

  • Diet – potassium rich foods encouraged and during periods of diarrhoea and vomiting electrolyte replacement is important
  • Implantable cardiac defibrillator – if survivor or prior cardiac arrest without reversible cause (not appropriate for Margaret as her LQTS is reversible).
  • Permanent Pacemaker for Long QT associated with bradycardia
  • Testing of family members for LQTS

Margaret’s trimethoprin therapy is discontinued and she is commenced on a beta-blocker. After 7 days in hospital she is discharged home.

Pulse point

Margaret is prescribed a beta-blocker. Beta-blockers cause an adrenergic blockade which decreases the effect of sympathetic stimulation of the heart. This diminishes the risk of cardiac arrhythmias. Beta-blockers have been shown to be effective in 70% of patients with LQTS.