All of these contraindications need to be reviewed in the context of the clinical presentation.
For further information on the use of tenecteplase see: electronic Medicines Compendium (eMC)
Q. Which of the following are contraindications to tenecteplase? (True/false quiz with explanation)
| Statement | True | False | Feedback |
|---|---|---|---|
| Systolic blood pressure > 160 mm Hg | Ô£ö | False, but severe uncontrolled hypertension is. | |
| Cerebrovascular disease | Ô£ö | False, only if TIA or CVA within the last 6 months. | |
| Gastrointestinal or genitourinary bleeding | Ô£ö | False, unless it is within the last 10 days | |
| Active peptic ulceration | Ô£ö | Active peptic ulceration has a risk of life threatening bleeding. | |
| Prolonged cardiopulmonary resuscitation (> 2 minutes) on presentation | Ô£ö | There is an increased risk of internal trauma and haemorrhage. | |
| Major surgery or significant trauma within the past 2 months(this includes any trauma associated with the current AMI) | Ô£ö | True, if occurred within the last 2 months |
Page last reviewed: 10 Jun 2020
